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3D Printing Model- General Embryo SMI-3DP-GE

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3D Printing Model- General Embryo SMI-3DP-GE

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Description

Constructing a multi-structured 3D digital anatomical model using high-precision digitized human body data. A full-color, multi-material 3D printer and environmentally friendly resin materials are used to create 1:1 highly accurate simulations of physical anatomical models.

Digital Human Model

The texture features of the unevenness of the skull base are clearly visible. All the holes, fissures, and protrusions that enter and exit the skull are accurately preserved, including the sieve holes, rupture holes, spinous holes, carotid canals, and other structures. The flat, thin, and slender structures such as the sphenoid pterygoid process, pear bone, inferior turbinate, and styloid process are also displayed with precision. Anatomical features like the foramen ovale, petrous part of the temporal bone, grooves, fissures, protrusions, depressions, holes, impressions, and other markers are clearly defined and distinguishable.

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Early Embryonic Stage (1-5 days) Ratio : 200:1

  • 1-day-old embryo: A fertilized egg with an outer hyaline band. Blastocyst size: 0.2 mm.
  • 2-day-old embryo: 2-cell stage, consisting of two ovoid spheres with an outer zona pellucida and 2 to 3 visible polar bodies. Blastocyst size: 0.2 mm.
  • 3-day-old embryo: Mulberry embryo, composed of approximately 16 ovoid spheres, resembling a mulberry, and covered with a zona pellucida. Blastocyst size: 0.2 mm.
  • 4-day-old embryo: Blastocyst, also known as a blastocyst, with the trophectoderm surrounding the blastocyst cavity, containing a cluster of inner cells at one end of the cavity and a zona pellucida around the blastocyst. Blastocyst size: 0.2 mm.
  • 5-day-old embryo: Blastocyst with zona pellucida removed. Blastocyst size: 0.25 mm.

Early embryonic stage (6-14 days) Ratio : 50 : 1

  • 6-day-old embryo: Onset of implantation, with the adhesion of the trophoblast end of the blastocyst to the endometrium. Blastocyst size: 0.25 mm.
  • 7-day-old embryo: Embryo in implantation, with the blastocyst partially entering the endometrium. The trophectoderm differentiates into the cytotrophoblast and syncytiotrophoblast. Blastocyst size: 0.25 mm.
  • 9-day-old embryo: The blastocyst penetrates deeply into the endometrium, and the implantation opening is sealed by a coagulation plug. The dictyostelium is formed, followed by the appearance of the amniotic sac and primary yolk sac. Trophectodermal traps form in the syncytiotrophoblast. Embryonic disc size: 0.2 mm.
  • 12-day-old embryo: Implantation is complete, and the implantation opening is covered by surface epithelium. The extraembryonic mesoderm and extraembryonic body cavity appear, and the trophectodermal trap is filled with maternal blood. Embryonic disc size: 0.3 mm.
  • 14-day-old embryo: Dictyostelium disc formation, secondary yolk sac formation, and degeneration of the primary yolk sac to form ectodermal cavity vesicles. The external corpora cavernosa and somites are clearly visible, and the primary chorion is formed. Embryonic disc size: 0.4 mm.

Embryonic stage (3-6 weeks) Ratio :10: 1

  • End of 3 weeks: Evolution of the discoid embryo to the barrel-shaped embryo, with the formation of cephalic, caudal, and lateral folds. The closure of the neural groove begins, and 4-8 pairs of somites form. Embryonic body length: 2.0 mm.
  • Early 4 weeks: Barrel-shaped embryo, with the neural sulcus continuing to close, and anterior and posterior neural pores visible. Body segments: 8-12 pairs. Embryo body length: 3.5 mm.
  • Mid 4 weeks: The embryo remains barrel-shaped, with the anterior neural pore closed and the posterior neural pore still open. The 1st, 2nd, and 3rd pairs of gill arches appear, along with the lens plate, auditory sulcus, cardiac rongeur, and caudal bud. Body segments: 13-21 pairs. Parietal rump length: 4.5 mm.
  • End of 4 weeks: Both anterior and posterior neuropores are closed. There are 21-30 pairs of somites, and the 1st, 2nd, and 3rd pairs of gill arches are present. Upper and lower limb buds appear, and the anterior cerebral prominence and oral concavity are clearly visible. Parietal rump length: 5.5 mm.
  • 5 weeks: The body segments reach more than 40 pairs, the 4th gill arch appears, the cardiac ramus is prominent, the upper limb buds are paddle-shaped, and the optic cup and outer ear primordium are visible. Terminal rump length: 8.0 mm.
  • 6 weeks: Finger (toe) ridges appear on the hand and foot plates, ear mounds are clearly visible, and physiological umbilical hernia is present. Parietal rump length: 13 mm.

Embryonic Stage (8 weeks) Ratio : 10 : 1 Top hip length: 30mm

Physiological features: Separation of fingers (toes), growth of upper and lower extremities, formation of elbow and knee flexion, development of the five senses and facial features, disappearance of the tail, and the continued presence of the umbilical hernia.

Fetal stage (3 months) Ratio :1: 1 Top hip length: 90mm

Physiological features: The physiological umbilical hernia disappears, the eyelids close, the sex of the external genitalia becomes recognizable, the eyes and ears approach their intrinsic position, and the nails and toenails appear successively.

Fetal stage (5 months) Ratio :1: 1 Top hip length: 190mm

Physiological features: Fetal fat and hair appear, the eyelids remain closed, and the fetal body is emaciated.

Fetal stage (7 months) Ratio: 1: 1 Top hip length: 270mm

Physiological features: Appearance of eyebrows, opening of eyelids, growth of hair, appearance of eyelashes, disappearance of the pupillary membrane, and reduction of skin folds.

Data Resources

Data Source: Data were selected from a high-precision digital human dataset, including original sectional data, refined segmentation data, and 3D geometric models of organ structures, such as bones, muscles, blood vessels, nerves, and ligaments. The voxel size of this dataset is 0.0384 mm * 0.0384 mm * 0.1 mm. Formalin-fixed cadaveric specimens were also used as a reference and comparison basis for the 3D printing model.

Model Creation: The voxels on the surface of each anatomical structure in the volume data were extracted from the original sectional dataset, and texture maps of the geometric models were generated to ensure that the appearance of each anatomical structure’s geometric model aligns visually with the real anatomical specimen.

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